| ncRNA name | mmu-miR-19a |
| ncRNA Category | miRNA |
| Disease name | retinoblastoma (RB) |
| Species | Mus musculus |
| Tissues/Cell_line | RB samples and normal retinas |
| Methods | microarray, Northern blot, RNA-seq, Array-CGH/ROMA analyses, immunohistochemistry, immunofluorescence, histology, qRT-PCR, Western blot |
| Expression pattern | up-regulated |
| Functional description | We found that deletion of Rb family members led to compensatory up-regulation of the cyclin-dependent kinase inhibitor p21Cip1. miR-17~92 overexpression counteracted p21Cip1 up-regulation, promoted proliferation, and drove retinoblastoma formation. |
| PubMed ID | 21816922 |
| Year | 2011 |
| Title | miR-17~92 cooperates with RB pathway mutations to promote retinoblastoma. |
| Drug-related ncRNA | NO |
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